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Fibrinogen (Serum) with Qualitative or Semi-Quantitative Assessment for Clotting Function

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibrinogen in your blood, a protein essential for blood clotting. Low levels may indicate bleeding disorders or liver issues, while high levels could be linked to inflammation or certain blood disorders.

Quick summary

["Fibrinogen helps your blood clot properly; abnormal levels may signal underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29263-1
Short code
FDP Bld Ql Aggl
Synonyms
FDP Bld Ql Aggl
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
aggl
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for bleeding problems, diagnose conditions like liver disease, or evaluate signs of inflammation or infection. It’s also used before surgeries to assess clotting risk.

What to Expect Before the Test

No special preparation is needed, but avoid strenuous activity 24 hours before. If you’re on blood thinners, inform your lab team beforehand.

How the Test Works

A blood sample is drawn from a vein, typically in your arm. The sample is sent to a lab where fibrinogen levels are measured using an immunoassay or similar method to detect clotting activity.

What the Results Mean

Results are qualitative (yes/no) or semi-quantitative (approximate range), not precise numbers. Low fibrinogen may suggest bleeding risks or liver dysfunction; high levels could point to inflammation or other conditions. Your doctor will interpret results in context of your health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Fibrinogen plays a critical role in blood clotting. Low levels may indicate inherited bleeding disorders (e.g., afibrinogenemia), liver disease, or severe infections. High levels can be associated with acute inflammation, chronic diseases, or certain blood disorders. Monitoring fibrinogen helps guide treatment for bleeding risks or clotting disorders.

Short name

Fibrinogen Test

Frequently asked questions

What causes low fibrinogen levels?
Low fibrinogen can result from liver disease (e.g., cirrhosis), severe infections, blood loss, or certain medications. It may also be present in inherited clotting disorders.
What causes high fibrinogen levels?
High fibrinogen is often linked to inflammation (e.g., infections, autoimmune diseases) or chronic conditions like cancer. Rarely, it may be genetic or due to dehydration.
Does this test require fasting?
No fasting is required for this test, but avoid alcohol or heavy meals 24 hours before to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy