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Folate Antibody (Serum) - Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies in your blood that may indicate an autoimmune response targeting folate, a vital nutrient for cell growth and DNA synthesis.

Quick summary

["Autoimmune antibodies to folate can sometimes be linked to certain health conditions and require further evaluation by your doctor."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
23733-9
Short code
FeLV Ab Ser Ql IF
Synonyms
FeLV Ab Ser Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like fatigue, anemia, or unexplained infections, or if you have conditions such as lupus or other autoimmune diseases. It may also be part of a broader evaluation for unexplained folate deficiency or immune-related disorders.

What Does the Test Involve?

A blood sample is taken from a vein in your arm. The sample is then analyzed in a lab using an immunoassay method to detect folate-specific antibodies.

What Are Normal Results?

There are no specific reference ranges provided for this test as results can vary by lab and method. Your results will be interpreted by your healthcare provider in the context of your overall health and symptoms.

What Are the Possible Results and What Do They Mean?

Positive results suggest the presence of antibodies against folate, which may indicate an autoimmune reaction. Negative results mean no detectable antibodies were found. Further testing and clinical correlation are essential to determine the cause and appropriate next steps.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Folate Antibody

Frequently asked questions

What does a positive result mean?
A positive result means your blood contains antibodies that target folate. This could suggest an autoimmune response or another underlying condition affecting folate metabolism. Your doctor will discuss this with you and may recommend additional tests or monitoring.
Can folate antibodies be treated?
There is no direct treatment for folate antibodies themselves. Management often focuses on addressing any underlying autoimmune conditions, managing symptoms, or monitoring closely. Your healthcare provider will tailor recommendations based on your specific situation.
Are folate antibodies common?
Folate antibodies are relatively rare and not commonly screened for in routine medical evaluations. They are more frequently checked in patients with suspected autoimmune diseases or unexplained deficiencies.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy