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Total Serum Protein (with Electrophoresis Profile)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood serum, including albumin and globulins, often used to diagnose conditions like kidney disease, liver problems, or infections.

Quick summary

["Assessing protein balance in your blood to identify potential health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61265-5
Short code
Fennel Seed IgE/IgE total %
Synonyms
Fennel Seed IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to check for abnormal protein levels, which can signal conditions such as kidney disease, liver disorders, infections, or certain cancers. It may also be used to monitor treatment progress or diagnose autoimmune diseases.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

The test separates proteins into bands (albumin, alpha, beta, and gamma globulins) using electrophoresis. Abnormal patterns may indicate conditions like multiple myeloma, autoimmune disorders, or nutritional deficiencies.

Common Conditions Monitored

This test helps detect protein abnormalities linked to diseases like chronic kidney disease, liver cirrhosis, or inflammatory conditions. It’s also used to evaluate protein loss in urine (e.g., nephrotic syndrome).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Protein Electrophoresis (SPE)

Frequently asked questions

What does a ‘total serum protein’ test measure?
It measures the overall concentration of proteins in your blood, including albumin and globulins, and provides a breakdown of their distribution via electrophoresis.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times.
Can I eat or drink before this test?
You can eat and drink normally unless instructed otherwise by your provider, as no fasting is required.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy