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Fentanyl in Plasma (24-hour Urine Collection)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of fentanyl, a powerful opioid pain medication, in your urine over a 24-hour period. It helps assess recent exposure or misuse.

Quick summary

["This test checks for recent opioid use, including misuse, by tracking fentanyl in your urine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
61077-4
Short code
fentaNYL Gast Ql
Synonyms
fentaNYL Gast Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’ve been prescribed fentanyl or other opioids, if you’re suspected of opioid misuse, or if you’re undergoing treatment for pain management or addiction. It can also be used to monitor compliance with treatment plans or detect accidental exposure.

What to Expect Before the Test

You’ll need to collect all urine produced in a 24-hour period in a special container. Typically, this starts after you first urinate in the morning of the collection day and continues until you urinate again the following morning. Follow your provider’s instructions carefully to ensure accurate results.

What Happens During the Test

No blood draw is needed for this test. Instead, you’ll provide a full 24-hour urine sample. The sample is then analyzed in a lab to measure the concentration of fentanyl.

What the Results Mean

Results are interpreted based on your clinical situation, such as whether you’re prescribed fentanyl or suspected of misuse. High levels may indicate recent use, while low or absent levels suggest no recent exposure. Your healthcare provider will discuss these results with you in detail.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urine Fentanyl

Frequently asked questions

How long does it take to get my test results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will contact you once results are ready.
Can I drink alcohol before this test?
Alcohol does not interfere with fentanyl urine tests, but it’s important to follow your provider’s instructions for the entire 24-hour collection period. Avoiding alcohol or other substances that might affect your health during this time can help ensure accurate results.
What if I miss any urine during the collection period?
If you miss any urine, you’ll need to restart the collection from the beginning. Missing even a small amount can affect the accuracy of the test results. Always check with your provider if you’re unsure about the collection process.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy