Fetal Achiral Carboxyterminal Cross-Linked Telopeptide (aCTX) in Serum/Plasma
This test measures a protein fragment produced during bone remodeling in fetal circulation. It helps assess bone health and development.
["Helps evaluate fetal bone formation and resorption rates during pregnancy."]
Key facts at a glance
- LOINC
- 11697-0
- Short code
- Fet Ac arch Vmax sys DOP
- Synonyms
- Fet Ac arch Vmax sys DOP
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- us-doppler
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you’re at risk for complications related to fetal bone development, such as preterm labor, fetal growth restriction, or conditions affecting skeletal development. It may also be used in cases of suspected fetal skeletal dysplasia or other congenital bone disorders.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample, typically drawn from a vein in your arm. The test is usually done during a routine prenatal visit or as part of a specialized fetal assessment.
What the Results Mean
Results are compared to reference ranges for fetal development at your specific gestational age. Elevated levels may indicate increased bone turnover, while lower levels could suggest reduced bone formation. Your provider will interpret results in the context of your pregnancy and medical history.
Common Reasons for Abnormal Results
High levels might suggest conditions like fetal skeletal dysplasia, growth restriction, or preterm labor risks. Low levels could be associated with slower bone development or certain genetic disorders. Always discuss any abnormal results with your healthcare provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is primarily used in high-risk pregnancies to monitor fetal skeletal health. It complements other prenatal tests, such as ultrasound or genetic screening, by providing additional data on bone metabolism. Early detection of abnormal bone turnover can help guide interventions to support fetal development.
Short name
Fetal Bone Turnover Marker
Frequently asked questions
What is fetal achiral carboxyterminal cross-linked telopeptide (aCTX)?
Will I need to do anything special before the test?
Can this test detect genetic bone disorders?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy