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Serum or plasma electrolytes panel with specific ion measurements (including sodium, potassium, chloride, bicarbonate, and possibly calcium)

Published: August 9, 2026Updated: August 16, 2026

This test measures key minerals and chemicals in your blood that help regulate important body functions, such as fluid balance and nerve signaling.

Quick summary

["Your blood chemistry helps doctors understand how well your organs are working and detect imbalances early."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11851-3
Short code
Fet Head OFD US.meas
Synonyms
Fet Head OFD US.meas
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-measured
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This panel typically includes measurements for sodium (Na⁺), potassium (K⁺), chloride (Cl⁻), and bicarbonate (HCO₃⁻), which are essential electrolytes. Some versions may also assess calcium levels. These substances help maintain fluid balance, nerve function, and muscle contractions.

Why It’s Ordered

Doctors may order this test to evaluate dehydration, kidney function, heart conditions, acid-base balance, or electrolyte imbalances. It’s often used in emergency settings or when monitoring chronic illnesses like diabetes or kidney disease.

Common Reasons for Testing

Common triggers include symptoms like excessive thirst, confusion, irregular heartbeat, muscle weakness, or unexplained fatigue. It may also be part of routine check-ups for high-risk patients or those on medications that affect electrolytes.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate serum or plasma (the liquid part) for testing. No special preparation is needed, but fasting may be required for some related tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Low sodium levels (hyponatremia) can cause headaches, nausea, or confusion, while high sodium levels (hypernatremia) may lead to weakness or seizures. Potassium imbalances can affect heart rhythm, while bicarbonate levels help diagnose acid-base disorders like metabolic acidosis or alkalosis.
What does a low or high sodium level mean? Low sodium can signal dehydration, kidney issues, or excessive fluid retention, while high sodium may indicate dehydration, heart problems, or overuse of certain medications.
How long does it take to get results? Results are typically available within 24 to 48 hours, depending on lab processing times and urgency.
Can I eat or drink before this test? Most patients can eat normally, but some tests (like glucose) require fasting. Always follow your doctor’s instructions.
Is there any risk or discomfort with this test? There’s minimal discomfort from the needle, but some people experience bruising or slight pain. Rarely, allergic reactions can occur.
Can I take this test at home? No, this test requires a lab sample, so it must be collected by a healthcare professional in a clinical setting.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy