Total Protein with Albumin-to-Globulin Ratio (Serum/Plasma)
This test measures your blood’s total protein levels and compares albumin to globulin proteins, which can help assess protein balance, kidney function, and potential nutritional or inflammatory conditions.
["Your blood proteins help maintain fluid balance and support immune function; this test provides insight into their overall health and ratios."]
Key facts at a glance
- LOINC
- 100875-4
- Short code
- Fet Hrt Doc Ltd US
- Synonyms
- Fet Hrt Doc Ltd US
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- us
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does Total Protein Measure?
Total protein includes both albumin and globulin proteins. Albumin helps regulate fluid balance in your body, while globulins support immune function and transport certain substances. Together, they reflect your body’s protein production and potential issues like malnutrition, liver disease, or kidney problems.
Why Might Your Doctor Order This Test?
Doctors may order this test to evaluate protein levels in conditions like malnutrition, kidney disease, liver disease, or chronic inflammation. It can also help monitor treatment responses for conditions affecting protein synthesis or breakdown.
How Is This Test Performed?
A blood sample is drawn from a vein, typically in your arm. The sample is sent to a lab where it is analyzed to measure total protein content and the ratio of albumin to globulin proteins. Results are compared to standard reference ranges for your age and health status.
What Are Common Causes of Abnormal Results?
Low total protein or abnormal ratios may indicate malnutrition, liver disease, kidney disease, or chronic infections. High levels could suggest dehydration, multiple myeloma, or severe inflammation. Always discuss your results with your healthcare provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Total Protein & AG Ratio
Frequently asked questions
What does a high or low total protein level mean?
How long does it take to get results from this test?
Can I eat or drink anything before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy