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Fetal hemoglobin concentration in maternal serum (measured by high-performance liquid chromatography)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fetal hemoglobin (HbF) in your blood serum. Fetal hemoglobin is a type of hemoglobin found in a baby’s blood before birth and for the first few months after birth.

Quick summary

["Assesses fetal hemoglobin levels in maternal blood, useful for certain prenatal conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11713-5
Short code
Fet LVOT Vmax sys DOP
Synonyms
Fet LVOT Vmax sys DOP
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-doppler
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have certain conditions that affect how your body produces hemoglobin, such as thalassemia or sickle cell disease. It can also help monitor fetal development in high-risk pregnancies.

What Does the Result Mean?

Results are not typically provided as a single numeric range since fetal hemoglobin levels vary widely. High levels may indicate conditions like fetal anemia or certain genetic disorders, while very low levels might suggest other health concerns.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The serum portion of your blood is then analyzed using high-performance liquid chromatography (HPLC) to measure fetal hemoglobin concentration.

What Are Common Causes for Testing?

This test is often performed during prenatal care to screen for genetic blood disorders or to assess fetal health in cases of high-risk pregnancies. It may also be used in research or specialized clinical settings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Fetal Hb (Serum)

Frequently asked questions

What does an abnormal fetal hemoglobin level mean?
An abnormal result doesn’t necessarily indicate a problem on its own, but it may signal the need for additional testing or evaluation by your healthcare provider to understand potential causes.
How often should I expect this test?
The frequency depends on your medical history and pregnancy status. Your healthcare provider will determine if and when this test is needed based on your specific situation.
Can I prepare for this test?
No special preparation is required. You may continue with your normal activities, but avoid excessive physical exertion before the blood draw.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy