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Fetal Nasal Bone Length Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the length of the fetal nasal bone during pregnancy using ultrasound imaging. It is often part of a screening process to assess certain genetic or chromosomal conditions.

Quick summary

["This test helps screen for potential genetic risks during pregnancy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53697-9
Short code
Fet Nasal bone Length US.meas
Synonyms
Fet Nasal bone Length US.meas
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-measured
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may recommend this test if you are at higher risk for conditions like Down syndrome, trisomy 13, or other chromosomal abnormalities. It is sometimes included in first-trimester screening, especially if you have risk factors such as advanced maternal age, family history of genetic disorders, or other medical conditions. This test is typically performed between 11 and 14 weeks of gestation using an ultrasound to visualize the fetal nasal bone.

How Is the Test Performed?

During the ultrasound, a transducer is placed on your abdomen to create images of your fetus. The provider will measure the length of the nasal bone, which appears as a small bony structure near the nose. This measurement is compared to standard ranges to determine if it falls within expected limits or if further evaluation is needed.

What Does the Result Mean?

A fetal nasal bone length that is shorter than expected may be associated with an increased risk of certain chromosomal conditions. However, it is not a definitive test for these conditions. Your provider will discuss the results with you and may recommend additional testing, such as amniocentesis or chorionic villus sampling, if needed. Results alone do not diagnose a condition; they are used as part of a broader evaluation.

What Are Possible Outcomes?

If the nasal bone length is within normal limits, it suggests no increased risk for the conditions being screened. If it is outside the normal range, further genetic counseling and testing may be advised to assess risks more thoroughly. This test is not diagnostic but is part of a screening process to identify potential concerns early.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Fetal Nasal Bone Length Screening

Frequently asked questions

What does a low nasal bone measurement indicate?
A shorter-than-expected nasal bone length may signal an increased likelihood of certain chromosomal abnormalities, such as Down syndrome or trisomy 13. However, it is not a definitive diagnosis. Your healthcare provider will interpret the result in the context of other screening tests and your overall health history.
Can this test detect all genetic conditions?
No, this test is a screening tool and cannot detect every genetic or chromosomal condition. It is used alongside other tests, such as maternal blood tests and ultrasound measurements, to provide a more comprehensive assessment of risks.
Is this test painful or uncomfortable?
No, this ultrasound test is not painful. You may feel a slight pressure or warmth where the transducer is placed, but it is generally comfortable and does not require preparation beyond what is typical for an ultrasound.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy