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Fetal Placental Growth Factor (Placental Growth Factor) Analysis

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of placental growth factor (PGF), a protein produced by the placenta that plays a key role in regulating blood flow and development during pregnancy.

Quick summary

["PGF helps assess placental health and potential risks in pregnancy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11946-1
Short code
Fet Placenta Grade US
Synonyms
Fet Placenta Grade US
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test if you’re at higher risk for complications like preeclampsia, placental insufficiency, or other pregnancy-related issues. It can also be used to monitor fetal well-being in certain cases, such as when there are concerns about growth restrictions or other placental problems.

When Might You Need This Test?

This test might be recommended during pregnancy if you have conditions like high blood pressure, diabetes, or a history of gestational hypertension. It may also be part of routine screening in high-risk pregnancies or if your doctor notices signs that suggest placental issues.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The blood is then sent to a lab for analysis to measure the placental growth factor levels.

What Do the Results Mean?

Results help evaluate placental function and may indicate whether additional monitoring or interventions are needed. Abnormal levels could signal potential risks to you or your baby, prompting further evaluation by your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Placental Growth Factor (PGF) Level

Frequently asked questions

What does a low placental growth factor level mean?
A low level may suggest potential placental issues, such as restricted blood flow or early signs of placental dysfunction. Your doctor will discuss next steps, which could include closer monitoring or additional tests to assess fetal and maternal health.
How often is this test repeated during pregnancy?
The frequency depends on your individual risk factors and pregnancy status. Your healthcare provider will determine if and when repeat testing is needed, often based on your symptoms, lab results, or other clinical findings.
Is this test painful or uncomfortable?
The blood draw is typically quick and may cause mild discomfort, but it’s not usually painful. Most people experience minimal discomfort afterward, similar to a small bruise or soreness at the injection site.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy