Skip to content

Fetal Presumptive Prenatal Screening Marker Panel (Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures certain substances in your blood to help assess the risk of certain birth defects or chromosomal conditions in your baby.

Quick summary

["A simple blood test to check for potential genetic or developmental concerns during pregnancy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
18850-8
Short code
Fet pres US
Synonyms
Fet pres US
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

This test typically includes markers such as non-invasive prenatal testing (NIPT)-related substances or other biochemical indicators that may suggest chromosomal abnormalities (e.g., Down syndrome) or neural tube defects. The results are used alongside other prenatal screening methods to provide a more comprehensive assessment.

Why Is This Test Done?

Your healthcare provider may recommend this test during the first or second trimester to evaluate the risk of certain genetic conditions. It helps guide decisions about further diagnostic testing if needed, such as amniocentesis or chorionic villus sampling.

How Is the Sample Collected?

A blood sample is drawn from your arm by a healthcare professional. This sample is processed into plasma and sent to a laboratory for analysis.

How Long Does It Take to Get Results?

Results are usually available within 1–2 weeks, depending on the laboratory and the specific markers being tested. Your healthcare provider will discuss the findings with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test provides a preliminary assessment of potential genetic risks but is not a definitive diagnostic tool. It is often used alongside other prenatal screening methods, such as ultrasound or maternal blood tests, to provide a more complete picture. If your results suggest an increased risk, further diagnostic testing may be recommended to confirm or rule out specific conditions.

Short name

Prenatal Plasma Screening

Frequently asked questions

What Are the Common Analytes Measured in This Test?
The exact analytes vary by lab, but may include substances like free beta-hCG, PAPP-A, or other biochemical markers related to fetal development. These are not always the same as those in standard NIPT and are used in a screening context rather than diagnostic.
Will This Test Replace Other Prenatal Screenings?
No, this test is typically used alongside other prenatal screening methods, such as ultrasound or maternal serum screening, to provide a more complete evaluation. It is not a standalone test for diagnosing genetic conditions.
What If My Results Are Abnormal?
If your results indicate an increased risk for certain conditions, your healthcare provider will discuss next steps, which may include additional testing or monitoring. Always follow your provider’s guidance for further evaluation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy