Fetal Protein: Alpha-Fetoprotein (AFP) in Amniotic Fluid Measurement

Why Is This Test Done?

Your healthcare provider may recommend this test during pregnancy if you have a higher risk of certain birth defects, such as spina bifida or anencephaly. It is also commonly offered as part of the first-trimester screening or second-trimester anomaly scan. Early detection can help guide further testing or monitoring.

What Does the Test Involve?

A small amount of amniotic fluid is collected through a procedure called an amniocentesis. The fluid is then sent to a lab for analysis. The test measures the concentration of AFP, which can provide important information about your baby’s health.

What Are the Possible Results?

Results are interpreted in the context of your pregnancy timeline and other screening tests. Low or high levels of AFP may indicate an increased risk for certain birth defects, prompting additional diagnostic tests or closer monitoring.

What Does a High or Low AFP Level Mean?

Elevated AFP levels may suggest conditions like neural tube defects or other chromosomal abnormalities. Lower levels might be associated with other risks, such as miscarriage or certain genetic syndromes. Your healthcare provider will discuss these findings with you.