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Fetal Fibrinogen Degradation Products (D-Dimer) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the breakdown products of fibrin, a protein involved in blood clotting. It helps assess whether you have an active blood clot or clotting disorder.

Quick summary

["D-Dimer helps diagnose conditions like deep vein thrombosis or pulmonary embolism by detecting clot breakdown."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11626-9
Short code
Fet Q2 AFI der US
Synonyms
Fet Q2 AFI der US
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-derived
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is D-Dimer Used For?

D-Dimer is primarily used to evaluate suspected blood clotting problems. It can help rule out conditions like deep vein thrombosis (blood clots in veins) or pulmonary embolism (clots in the lungs) when combined with other tests and clinical findings.

How Is This Test Performed?

A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate serum (the liquid part after clotting) for testing. The test detects the presence of D-Dimer fragments, which form when clots dissolve in the body.

What Might Influence Results?

Several factors can affect D-Dimer levels, including recent blood clotting events, pregnancy, certain medications (like anticoagulants), infections, or inflammatory conditions. Always discuss your medical history with your healthcare provider.

When Might You Need This Test?

Your doctor may recommend a D-Dimer test if you have symptoms like swelling, pain in your legs, shortness of breath, or chest pain that could suggest a blood clot. It may also be used as part of a screening or diagnostic workup for clotting disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Why Does This Test Matter?

Short name

D-Dimer (Serum)

Frequently asked questions

Why was I asked to have this test?
Your doctor may have ordered this test to check for signs of blood clots, such as deep vein thrombosis or pulmonary embolism. High levels of D-Dimer can indicate recent clot formation, while low or absent levels may suggest no active clotting process.
What do my results mean?
Results can be complex and depend on your symptoms, medical history, and other tests. Very high levels may raise concern for clotting, while very low levels might mean no clot activity. Always discuss your specific results with your healthcare provider.
Can I do anything to prepare for this test?
No special preparation is needed, but avoid heavy meals or strenuous activity before the blood draw. If you’re on blood-thinning medication, let your doctor know before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy