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Fetal Fibrinogen Degradation Products (D-Dimer) in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the breakdown products of fibrin, a protein involved in blood clotting. It helps assess whether you’re at risk for blood clots or clotting disorders.

Quick summary

["A D-Dimer test can help diagnose conditions like deep vein thrombosis (blood clots in veins) or pulmonary embolism (clots in the lungs)."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11625-1
Short code
Fet Q3 AFI der US
Synonyms
Fet Q3 AFI der US
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-derived
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is a D-Dimer Test Used For?

Doctors use this test primarily to evaluate suspected blood clots. High levels may suggest conditions like deep vein thrombosis (DVT) or pulmonary embolism, while low or absent levels help rule out these clotting events. It’s often part of a broader diagnostic workup.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The blood is then processed to separate serum or plasma, which is tested for the presence of D-Dimer fragments using a sensitive immunoassay method.

What Does a High or Low Result Mean?

Results can vary based on medical conditions. Very high levels may indicate active clotting disorders, while very low or negative results often mean no clotting activity is present. However, results alone aren’t diagnostic—they’re usually interpreted alongside other test results and clinical findings.

Common Conditions That May Affect Results

Factors like pregnancy, certain cancers, infections, or inflammatory conditions can influence D-Dimer levels. If you have a history of clotting disorders or are on blood thinners, your results may differ from someone without these conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

D-Dimer (Serum/Plasma)

Frequently asked questions

Why was I asked to have this test?
Your doctor may recommend this test if you have symptoms like swelling, pain in your legs (possible DVT), chest pain (possible pulmonary embolism), or if you’ve been diagnosed with a clotting disorder. It helps guide treatment decisions.
What do my results mean for my health?
High results may prompt further testing or treatment to prevent or manage clots, while low results could mean no immediate concern. Always discuss your results with your healthcare provider.
Can I eat or drink before this test?
You can eat and drink normally before this test, as it doesn’t require fasting. However, inform your doctor about any medications or supplements you’re taking, as they may affect results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy