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: Fetal Hemoglobin, Blood, Measured

Published: August 9, 2026Updated: August 16, 2026

: This test measures the amount of fetal hemoglobin (hemoglobin F) in a blood sample. Fetal hemoglobin is the form of hemoglobin that carries oxygen in a developing baby, and small amounts can persist after birth.

Quick summary

[": Measuring fetal hemoglobin helps evaluate certain anemias and inherited blood conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11812-5
Short code
Fet SB Diam US.meas
Synonyms
Fet SB Diam US.meas
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-measured
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What Is Fetal Hemoglobin?

: Hemoglobin is the protein in red blood cells that carries oxygen. Fetal hemoglobin, or hemoglobin F, is the main oxygen-carrying hemoglobin before birth and is gradually replaced by adult hemoglobin after birth. Most older children and adults have only small amounts of fetal hemoglobin remaining.

: Why This Test Is Done

: A fetal hemoglobin measurement may be ordered to help assess inherited blood disorders such as thalassemia or sickle cell disease, to evaluate certain types of anemia, or to monitor conditions in which fetal hemoglobin levels are unusually high. It can also be used as part of follow-up when abnormal hemoglobin is found.

: How the Sample Is Collected

: The test is usually performed on a blood sample drawn from a vein, typically from the arm. The specimen may be analyzed by a laboratory method that separates and measures the different hemoglobin types present.

: What the Results Mean

: Results are interpreted alongside your age, symptoms, family history, and other blood tests. A higher-than-expected fetal hemoglobin level may occur in several inherited and acquired conditions, so the result is considered together with the full clinical picture rather than on its own.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

: HbF

Frequently asked questions

: Does everyone have some fetal hemoglobin?
: Yes. Most healthy adults have a small amount of fetal hemoglobin remaining, but the typical amount is low. Levels that are higher than expected can be a clue to certain blood conditions and should be reviewed with your clinician.
: Does this test diagnose sickle cell disease or thalassemia?
: Not by itself. Fetal hemoglobin measurement provides one piece of information. Diagnosing these conditions usually requires additional hemoglobin testing and review by a healthcare professional.
: Do I need to fast or prepare for this test?
: In most cases no special preparation is required for a fetal hemoglobin measurement, but follow any instructions given by your ordering provider or laboratory, since preparation can depend on what other tests are being done at the same time.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy