Fibrinogen Total Concentration (Serum)
This test measures the amount of fibrinogen, a protein in your blood that helps form clots. It’s important for preventing excessive bleeding and supporting normal blood clotting function.
["Fibrinogen helps your blood clot properly—low levels may increase bleeding risk, while high levels could raise clot formation risk."]
Key facts at a glance
- LOINC
- 53678-9
- Short code
- Fet Tibia-R Length US.meas
- Synonyms
- Fet Tibia-R Length US.meas
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- us-measured
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your doctor may recommend this test if you have symptoms like easy bruising, prolonged bleeding from cuts, or if you’re undergoing surgery or a procedure. It’s also checked in conditions like liver disease, where fibrinogen production can be affected, or in cases of suspected clotting disorders.
What to Expect Before the Test
No special preparation is needed, but avoid aspirin or other blood-thinning medications for at least 7–10 days before testing, as they can affect clot formation. Fasted or non-fasted blood draws are typically okay, but check with your lab for specifics.
What Happens During the Test
A small needle will draw blood from a vein in your arm. You may feel a slight pinch, but it’s usually over quickly. The blood is sent to a lab for analysis, where fibrinogen levels are measured using a specialized test that detects its presence in your serum.
What the Results Mean
Results are reported as a concentration value (e.g., grams per liter). While reference ranges vary by lab, very low levels may suggest bleeding disorders or liver issues, while very high levels could indicate inflammation, pregnancy, or other conditions. Your doctor will interpret results in the context of your health.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Fibrinogen plays a critical role in hemostasis (blood clotting). Low levels can lead to conditions like von Willebrand disease or liver cirrhosis, increasing bleeding risks. High levels may signal acute-phase reactions (e.g., infections, trauma) or conditions like multiple myeloma. Monitoring fibrinogen helps guide treatment for bleeding disorders or clotting risks.
Short name
Fibrinogen Level
Frequently asked questions
What causes low fibrinogen levels?
What causes high fibrinogen levels?
Can diet affect fibrinogen levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy