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Fetal Serum/Plasma Creatinine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in fetal blood or amniotic fluid. It helps assess kidney function in a fetus.

Quick summary

["Creatinine levels can indicate how well the fetus’s kidneys are filtering waste."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11878-6
Short code
# Fetuses US
Synonyms
# Fetuses US
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re at risk for fetal kidney issues, such as during pregnancy with conditions like gestational diabetes, preeclampsia, or if there are signs of reduced fetal movement or growth problems. It may also be part of routine monitoring in certain high-risk pregnancies.

What to Expect Before the Test

For fetal blood testing, this may be done through procedures like a cord blood sample or amniocentesis. For amniotic fluid testing, a small amount is collected via a needle. You’ll likely receive instructions to avoid certain activities or medications before the procedure.

What the Test Results Mean

Results are compared to expected ranges for gestational age. Abnormally low levels may suggest kidney problems, while very high levels could indicate other conditions requiring further evaluation.

Common Causes of Abnormal Results

Low levels might indicate fetal kidney dysfunction, while high levels could be due to dehydration, certain medications, or other metabolic factors. Always discuss results with your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Fetal Creatinine Level

Frequently asked questions

How often will I need this test?
This test is typically done once or a few times during pregnancy, depending on your risk factors and the results of earlier tests. Your healthcare provider will determine the timing and frequency based on your specific situation.
What does a normal result mean for my baby’s health?
A normal result suggests that the fetus’s kidneys are functioning appropriately for their gestational age. However, no single test confirms overall health, so ongoing monitoring is essential.
Can I eat or drink before this test?
For fetal blood tests, you may need to follow specific fasting or preparation instructions depending on the procedure. For amniotic fluid tests, you’ll likely avoid food or fluids for a short time before the procedure, but always confirm with your provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy