Folate and Vitamin B12 Screening Panel (Serum)

Why This Test Matters

Vitamin B12 and folate are critical for DNA synthesis, red blood cell formation, and maintaining nerve health. Deficiencies can lead to anemia, weakness, or even long-term nerve damage. This screening helps identify potential deficiencies early, especially in people with risk factors like poor diet, alcohol use, or certain medical conditions.

How the Test Works

Blood is drawn from your arm and sent to a lab. The test measures the concentration of folate and vitamin B12 in your serum. Results help determine if you need additional testing or dietary adjustments.

What to Expect Before the Test

No special preparation is needed, but avoid heavy meals 2 hours before your appointment. Wear comfortable clothing if you need an arm restraint. If you’re pregnant, discuss this test with your provider—it’s often recommended during pregnancy.

Common Causes of Low Levels

Low folate or vitamin B12 levels may result from poor diet (e.g., vegan/vegetarian diets), alcohol use, certain medications (like proton pump inhibitors), or conditions like celiac disease or Crohn’s disease. Older adults, those with malabsorption issues, or individuals with chronic illnesses may also be at higher risk.