Genetic Mutation Analysis of Fibroblast Growth Factor Receptor (FGFR) in Whole Blood
This test checks for specific genetic changes in the FGFR gene that may be linked to certain cancers or inherited conditions. It uses a sample of your blood to identify mutations that could affect how your body functions at a cellular level.
["This test helps doctors understand if a genetic mutation in your FGFR gene may be contributing to your health concerns."]
Key facts at a glance
- LOINC
- 106872-5
- Short code
- FGFR gene Mut Tested Bld/T
- Synonyms
- FGFR gene Mut Tested Bld/T
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms or a family history suggestive of conditions like fibrodysplasia ossificans progressiva (FOP), certain types of cancer (e.g., squamous cell carcinoma), or other genetic disorders linked to FGFR mutations. It may also be used as part of a broader genetic screening or diagnostic workup.
How the Test Works
Blood is drawn from a vein in your arm. The sample is then analyzed to detect specific mutations in the FGFR gene. Advanced laboratory techniques, such as next-generation sequencing, are used to identify these genetic variations.
What to Expect Before the Test
No special preparation is typically needed for this test. You may be asked to fast or avoid certain medications, but your provider will give specific instructions if applicable. Bring a list of your current medications to your appointment.
What to Expect During the Test
The blood draw is quick and usually painless. You may feel a slight pinch or discomfort, but most people tolerate it well. You can resume normal activities immediately after the procedure.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
FGFR mutations can play a role in various health conditions, including cancers like non-small cell lung cancer, head and neck squamous cell carcinoma, and certain types of sarcoma. They may also be associated with inherited disorders like FOP, which causes abnormal bone growth. Identifying these mutations can help guide treatment decisions, such as targeted therapies or genetic counseling.
Short name
FGFR Gene Mutation Test (blood)
Frequently asked questions
What does a positive result mean?
Will this test affect my treatment options?
How long will it take to get my results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy