Fibrillarin Antibody, Serum (Qualitative Immunoassay)
This test checks for the presence of antibodies against fibrillarin, a protein found in certain cells involved in genetic activity. It may be used to evaluate autoimmune conditions affecting these cells.
["This test helps identify potential autoimmune responses linked to rare genetic disorders."]
Key facts at a glance
- LOINC
- 53005-5
- Short code
- Fibrillarin Ab Ser Ql IF
- Synonyms
- Fibrillarin Ab Ser Ql IF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- if
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms or conditions associated with autoimmune diseases targeting ribonucleoprotein particles, such as systemic sclerosis (scleroderma) or other connective tissue disorders. It may also be used in research or specialized diagnostic settings for rare genetic conditions.
What to Expect Before the Test
No special preparation is typically needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners or have a history of bleeding issues, let your provider know before the test.
What the Test Results Mean
Results are qualitative (positive or negative). A positive result indicates the presence of antibodies against fibrillarin, which may suggest an autoimmune response. Results alone don’t diagnose a specific condition but can guide further testing or treatment planning.
Common Conditions Monitored
This test is often used in conjunction with other diagnostic tools to investigate autoimmune diseases affecting ribonucleoprotein particles, such as systemic sclerosis (scleroderma) or other connective tissue disorders. It may also be part of research studies for rare genetic or autoimmune conditions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Fibrillarin Antibody Test
Frequently asked questions
What are the normal reference ranges for this test?
How long does it take to get my test results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy