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Fibrinogen (Serum or Plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of fibrinogen, a protein in your blood that helps form clots when you bleed.

Quick summary

["Fibrinogen helps control bleeding and supports blood clotting—low levels may increase bleeding risk; high levels may raise clot risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
60278-9
Short code
Fibrinogen Ag Tiss Ql IF
Synonyms
Fibrinogen Ag Tiss Ql IF
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
200
Ref high
400
Critical range
60 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
85384
SNOMED
47279000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for bleeding disorders, monitor blood clotting problems, or evaluate conditions like liver disease, kidney disease, or infections that can affect fibrinogen levels.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood, or a sample may be collected from a vein. If you’re on blood thinners, discuss this with your provider first.

What the Results Mean

Results are compared to a general reference range, but your actual values may vary based on health, age, and other factors. Abnormal levels could signal conditions like clotting disorders, liver disease, or infections.

Common Conditions Linked to Fibrinogen

Low fibrinogen may be linked to conditions like liver disease (where the body can’t produce enough), severe infections, or certain blood disorders. High levels could be seen in chronic inflammation, pregnancy, or some clotting disorders.

Reference range

Adult: 200-400 mg/dLN/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fibrinogen plays a key role in blood clotting and wound healing. Low levels may increase bleeding risk, while high levels could raise the chance of clots forming in veins or arteries. Regular monitoring may be needed if you have conditions like liver disease or clotting disorders.

Short name

Fibrinogen

Frequently asked questions

What causes low fibrinogen levels?
Low fibrinogen can result from liver disease (where the body can’t make enough), severe infections, blood loss, or certain medications. It may also appear in conditions like DIC (disseminated intravascular coagulation).
What causes high fibrinogen levels?
High fibrinogen is sometimes seen in chronic inflammation, infections, pregnancy, or certain cancers. It may also appear in response to stress or trauma. Your doctor will review your full medical history to understand why.
Can diet affect fibrinogen levels?
Dietary factors like high saturated fat intake or certain supplements may influence fibrinogen indirectly, but direct effects aren’t well-documented. Focus on overall health, hydration, and managing chronic conditions for balanced results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy