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Fibrinogen (Serum) Concentration

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of fibrinogen, a protein in your blood that helps form clots to stop bleeding.

Quick summary

["Fibrinogen helps your blood clot and supports wound healing. Low levels may increase bleeding risk; high levels may raise clot risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
10523-9
Short code
Fibrinogen Ag Tiss Ql ImStn
Synonyms
Fibrinogen Ag Tiss Ql ImStn
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
200
Ref high
400
Critical range
60 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-stain
CPT
85384
SNOMED
47279000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may order this test to check for bleeding disorders, clotting problems, or conditions like liver disease, which can affect fibrinogen production. It may also be done before surgery to assess your risk of bleeding.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Results are compared to a general reference range for healthy adults. Very low levels may suggest bleeding disorders or liver issues, while very high levels could indicate inflammation or clotting disorders.

Common Conditions Affecting Results

Conditions like liver disease, kidney problems, or infections can lower fibrinogen. Conditions like multiple myeloma or severe inflammation may raise it. Chronic diseases like diabetes or heart disease can also influence levels.

Reference range

Adult: 200-400 mg/dLN/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Fibrinogen

Frequently asked questions

How does fibrinogen relate to my health?
Fibrinogen is crucial for blood clotting. Low levels may indicate bleeding risks, while high levels could signal inflammation or clotting tendencies. Your doctor will use these results alongside other factors to guide treatment.
What if my results are outside the normal range?
If your results are outside the normal range, your doctor will discuss potential causes and next steps, such as further testing or changes to your treatment plan. They may also recommend lifestyle adjustments or monitoring.
Can I eat or drink before this test?
You can eat and drink normally before this test, unless your doctor has specific instructions. Avoiding alcohol or certain medications may be advised if you’re on blood thinners or have a condition affecting clotting.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy