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Fibrinogen (Quantitative)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of fibrinogen in your blood, a protein essential for blood clotting.

Quick summary

["Fibrinogen helps your blood clot properly and supports wound healing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
3259-9
Short code
Fibrinogen Frg Ag PPP IA-aCnc
Synonyms
Fibrinogen Frg Ag PPP IA-aCnc
Category
coagulation
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
200
Ref high
400
Critical range
60 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
85384
SNOMED
47279000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may check your fibrinogen level if you have symptoms of bleeding disorders, clotting issues, or conditions like liver disease, which can affect protein production. It may also be used to monitor treatment for conditions like disseminated intravascular coagulation (DIC) or to assess risk for blood clots in certain situations.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s drawn from serum, but plasma samples may not require fasting. Avoid aspirin or other blood thinners for 48 hours before testing if instructed by your provider.

How the Test Is Performed

A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate fibrinogen from other components, often using a method like nephelometry or turbidimetry to measure its concentration.

What the Results Mean

Results are compared to a general reference range, but exact values can vary by lab. Low levels may indicate bleeding disorders or liver disease, while very high levels could suggest conditions like multiple myeloma or acute-phase responses (e.g., infection).

Reference range

Adult: 200-400 mg/dLN/A

Specimen: plasma

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fibrinogen plays a critical role in hemostasis (blood clotting). Low levels can increase bleeding risk, while high levels may signal inflammation, infection, or certain cancers. Monitoring fibrinogen helps diagnose and manage conditions affecting blood clotting or protein synthesis.

Short name

Fibrinogen Level

Frequently asked questions

What causes low fibrinogen levels?
Low fibrinogen can result from liver disease (which impairs protein production), severe infections, blood loss, or certain medications. It may also appear in conditions like DIC, where the body forms clots uncontrollably.
What causes high fibrinogen levels?
High fibrinogen is often linked to inflammation, infections, or malignancies like multiple myeloma. It can also rise during pregnancy or in response to stress or trauma.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Follow-up with your provider to discuss findings and next steps.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy