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Fibrinogen (Mass Concentration) in Plasma

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of fibrinogen, a protein in your blood that plays a key role in blood clotting.

Quick summary

["Fibrinogen helps prevent excessive bleeding by forming clots when needed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
27990-1
Short code
Fibrinogen Frg PPP LA-mCnc
Synonyms
Fibrinogen Frg PPP LA-mCnc
Category
coagulation
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
200
Ref high
400
Critical range
60 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
la
CPT
85384
SNOMED
47279000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for blood clotting disorders, monitor treatment for conditions like liver disease or kidney problems, or evaluate bleeding risks before surgery. It can also help diagnose or monitor conditions affecting protein production or blood vessel health.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into a vein in your arm to draw blood. If you’re on blood-thinning medication, let your provider know before the test.

What the Results Mean

Results are typically reported in grams per deciliter (g/dL). Low levels may suggest bleeding disorders, liver disease, or malnutrition, while very high levels could indicate inflammation, pregnancy, or certain blood disorders.

Common Conditions Monitored

This test is often used to monitor patients with conditions like disseminated intravascular coagulation (DIC), liver cirrhosis, or those receiving blood-thinning therapies. It can also help assess bleeding risks in people with hemophilia or other clotting disorders.

Reference range

Adult: 200-400 mg/dLN/A

Specimen: plasma

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Plasma Fibrinogen

Frequently asked questions

How often will I need this test?
The frequency depends on your health condition and treatment plan. Your provider will determine how often to check your fibrinogen levels based on your specific needs, such as whether you’re recovering from surgery or managing a chronic illness.
Can diet affect my fibrinogen levels?
Dietary factors like high-fat foods, obesity, or certain chronic illnesses (e.g., diabetes) may influence fibrinogen levels, but the relationship isn’t as straightforward as other blood tests. Your provider will consider overall health, not just diet, when interpreting results.
What if my results are outside the normal range?
If your fibrinogen is low, your provider may recommend further testing or treatments to address underlying causes like liver disease or malnutrition. If it’s high, they might investigate conditions like inflammation or pregnancy. Always discuss results with your healthcare team.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy