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Fibrinogen (Mass Concentration) in Serum or Plasma

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of fibrinogen, a protein in your blood that helps form blood clots.

Quick summary

["Fibrinogen supports healthy blood clotting and can indicate bleeding or clotting risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
3255-7
Short code
Fibrinogen PPP-mCnc
Synonyms
Fibrinogen PPP-mCnc
Category
coagulation
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
200
Ref high
400
Critical range
60 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag
CPT
85384
SNOMED
47279000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for conditions affecting blood clotting, such as bleeding disorders, liver disease, or to monitor treatment for conditions like disseminated intravascular coagulation (DIC). It can also help diagnose or evaluate certain cancers or infections.

What Does a Low or High Level Mean?

Low fibrinogen levels may suggest bleeding disorders, liver problems, or severe infections. High levels could indicate conditions like multiple myeloma, pregnancy, or certain inflammatory diseases.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is then processed to separate serum or plasma for testing.

What Are Common Causes of Abnormal Results?

Changes in fibrinogen can result from medical conditions (e.g., liver disease, cancer), medications (e.g., anticoagulants), or certain genetic factors. Lifestyle factors like diet or stress may also play a role.

Reference range

Adult: 200-400 mg/dLN/A

Specimen: plasma

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fibrinogen plays a critical role in blood clotting and is produced primarily in the liver. Abnormal levels can signal underlying health issues that require medical attention, such as bleeding risks or clotting disorders. Regular monitoring may be needed for patients with chronic conditions affecting fibrinogen production or function.

Short name

Fibrinogen Level

Frequently asked questions

What does a normal range of fibrinogen mean for me?
A normal range doesn’t mean your blood is perfectly healthy—it just means your fibrinogen level falls within typical values for most people. Your doctor will consider your overall health and symptoms when interpreting results.
Can diet or supplements affect fibrinogen levels?
Some foods rich in vitamin K (like leafy greens) or omega-3s (found in fish) may influence clotting factors, including fibrinogen. However, the impact on fibrinogen itself is less direct. Always discuss supplements with your doctor.
How often should I get this test?
Your doctor will determine how often you need this test based on your medical history, symptoms, and treatment plan. Follow-up may be scheduled if you have conditions like liver disease or cancer.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy