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Fibrinogen (Mass Concentration in Plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of fibrinogen, a protein in your blood that plays a key role in blood clotting.

Quick summary

["Fibrinogen helps your blood clot properly and supports wound healing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
42568-6
Short code
Fibrinogen PPP-msCnc
Synonyms
Fibrinogen PPP-msCnc
Category
coagulation
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
200
Ref high
400
Critical range
60 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag
CPT
85384
SNOMED
47279000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your doctor may order this test to check for bleeding disorders, clotting issues, or to monitor conditions like liver disease, kidney disease, or certain cancers. It can also help evaluate responses to treatments for these conditions.

What Does a Low or High Fibrinogen Level Mean?

Low levels may suggest bleeding problems, liver disease, or severe infections. High levels could indicate inflammation, clotting disorders, or certain cancers. However, reference ranges vary by lab and individual health.

How Is This Test Done?

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate plasma, where fibrinogen is measured using a specialized lab technique.

What Should You Do Before the Test?

Avoid taking medications that affect clotting (like aspirin or blood thinners) unless your doctor advises otherwise. Eat and drink normally, as fasting may not be required.

Reference range

Adult: 200-400 mg/dLN/A

Specimen: plasma

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fibrinogen levels can be affected by conditions like liver disease, infections, or severe trauma, which can alter protein production or clotting function. Chronic diseases, pregnancy, and certain medications may also influence results.

Short name

Fibrinogen

Frequently asked questions

Will I feel any discomfort during the blood draw?
You may feel a slight pinch or sting when the needle is inserted, but it usually goes away quickly. Most people experience minimal discomfort afterward.
Can I eat or drink before this test?
Typically, no fasting is required for this test, but always follow your doctor’s instructions. If they specify otherwise, do so to ensure accurate results.
How long will it take to get my results?
Results are usually available within a few days to a week, depending on your lab’s processing time. Follow up with your doctor if you have questions about your results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy