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Fibrinogen (Plasma Protein Profile)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of fibrinogen in your blood, a protein crucial for blood clotting. Low levels may increase bleeding risk, while high levels could signal conditions like inflammation or liver disease.

Quick summary

["Fibrinogen helps control bleeding and supports blood clot formation—your levels may affect how easily you bleed or clot."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
16859-1
Short code
Fibrinogen PPP Ql
Synonyms
Fibrinogen PPP Ql
Category
coagulation
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
200
Ref high
400
Critical range
60 N/A – —
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85384
SNOMED
47279000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like easy bruising, excessive bleeding (e.g., nosebleeds, heavy periods), unexplained bruises, or if you’re undergoing surgery or a procedure. It may also be checked to monitor conditions like liver disease, inflammation, or blood disorders.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your doctor know beforehand.

What the Results Mean

Results are compared to a general range for healthy adults, but your doctor will interpret them based on your health history and symptoms. Very low or very high levels may need further investigation.

Common Conditions Affecting Fibrinogen

Low fibrinogen can occur with liver disease, severe infections, or blood disorders like von Willebrand disease. High levels may be linked to inflammation, pregnancy, or certain cancers.

Reference range

Adult: 200-400 mg/dLN/A

Specimen: plasma

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fibrinogen plays a key role in blood clotting and wound healing. Abnormal levels can increase bleeding risks or indicate underlying health issues like liver dysfunction or chronic inflammation.

Short name

Fibrinogen Level

Frequently asked questions

What causes abnormal fibrinogen levels?
Factors like liver disease, infections, inflammation, pregnancy, or certain medications (e.g., blood thinners) can affect fibrinogen. Genetic conditions or blood disorders may also play a role.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab. Your doctor will discuss them with you.
Can I eat or drink before this test?
You can eat and drink normally unless instructed otherwise. Avoid alcohol before blood draws to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy