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Serum Fibronectin Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibronectin, a protein produced by the liver and found in blood plasma. It helps assess liver function and the body’s ability to heal wounds.

Quick summary

["Fibronectin helps your body heal and supports liver health—low levels may signal problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14095-4
Short code
Fibronectin Aggr IgG Ser-aCnc
Synonyms
Fibronectin Aggr IgG Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to evaluate liver disease, kidney problems, or wound healing. Low fibronectin levels can indicate conditions like cirrhosis, severe infections, or malnutrition.

What Does a Result Mean?

Results may be below normal if your liver isn’t producing enough fibronectin (e.g., due to liver damage) or if your body is losing protein through illness. High levels may rarely suggest inflammation or certain immune responses.

Common Conditions Linked to Fibronectin Levels

Low fibronectin is often seen in chronic liver disease, severe infections, or malnutrition. It may also appear in kidney disease or after major trauma.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab to measure fibronectin using a specialized immunoassay method.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Fibronectin Level

Frequently asked questions

What causes fibronectin levels to be low?
Low fibronectin levels can result from liver disease (such as cirrhosis), severe infections, malnutrition, or conditions that cause excessive protein loss (like kidney disease). Stress or trauma may also temporarily affect levels.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will explain the meaning of your specific result.
Can diet affect fibronectin levels?
Dietary changes alone won’t directly alter fibronectin levels, but poor nutrition (e.g., low protein intake) may contribute to low levels. Focus on overall health and follow your doctor’s recommendations.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy