Skip to content

Serum Fibronectin Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibronectin, a protein produced by the liver that helps blood clot and supports tissue repair. It may be checked to assess liver function, kidney health, or wound healing.

Quick summary

["Fibronectin helps your body heal and controls blood clotting—low levels may signal organ damage or poor healing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
16867-4
Short code
Fibronectin Aggr IgG Ser-mCnc
Synonyms
Fibronectin Aggr IgG Ser-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you have symptoms like easy bruising, slow wound healing, or signs of liver or kidney problems. It can also help monitor conditions like cirrhosis, kidney disease, or certain infections.

What Does a Low or High Level Mean?

Low levels of fibronectin might indicate liver disease, kidney failure, or severe infections. Very high levels could rarely suggest inflammation or certain blood disorders, but this is less common.

How Is the Sample Collected?

A blood sample is drawn from a vein, usually in your arm. The blood is then sent to a lab to measure fibronectin levels.

What Should You Expect Before the Test?

No special preparation is needed, but avoid eating or drinking anything for 8–12 hours before the test if instructed. Wear comfortable clothing and let your doctor know about any medications or health conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Fibronectin

Frequently asked questions

Fibronectin is a key protein in blood clotting and tissue repair. Low levels can signal liver dysfunction, kidney damage, or poor wound healing, while abnormal spikes may rarely indicate inflammation or rare blood disorders. Your doctor will interpret results in the context of your overall health.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time.
What are the most common reasons doctors order this test?
Doctors may order fibronectin testing to evaluate liver function, kidney health, or wound healing in patients with symptoms like bruising, slow-healing wounds, or signs of systemic inflammation.
Follow your doctor’s instructions—usually avoid food/drink for 8–12 hours before drawing blood, but confirm with your lab or provider.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy