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Fibrinogen (Serum) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibrinogen, a protein in your blood that plays a key role in blood clotting.

Quick summary

["Fibrinogen helps your blood clot properly and supports wound healing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
23727-1
Short code
FIPV Ab Ser Ql IF
Synonyms
FIPV Ab Ser Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Fibrinogen?

Fibrinogen is a natural protein produced by your liver. It’s essential for blood clotting, helping to stop bleeding when you get injured. Low levels can increase your risk of bleeding too easily, while high levels may raise the risk of blood clots. This test helps doctors assess your clotting ability and overall blood health.

Why Might You Need This Test?

Your doctor may order a serum fibrinogen test if you have symptoms like easy bruising, excessive bleeding, or a history of clotting problems. It’s also used in monitoring conditions like liver disease, kidney disease, or after surgeries or medical treatments that affect blood clotting.

How Is the Test Done?

A small blood sample is taken from a vein, usually in your arm. The blood is then sent to a lab to measure fibrinogen levels. No special preparation is usually needed, but you may be asked to avoid certain medications or activities for a few days before testing.

What Do the Results Mean?

Results are reported as a concentration value (e.g., grams per liter). While reference ranges vary by lab, very low levels may suggest bleeding disorders or liver issues, while very high levels could indicate inflammation, infection, or clotting disorders. Your doctor will interpret results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Fibrinogen

Frequently asked questions

What causes low fibrinogen levels?
Low fibrinogen can result from liver disease (where the body can’t produce enough), severe infections or inflammation, blood loss, or certain medications or treatments that affect clotting. It may also appear in conditions like DIC or after trauma.
What causes high fibrinogen levels?
High fibrinogen is often linked to inflammation, infections, or pregnancy. Rarely, it can be caused by certain cancers or genetic disorders. Your doctor may also check levels if you have symptoms like fever, swelling, or unexplained weight loss.
How often should I get this test?
The frequency depends on your health condition. If you have a chronic illness like liver disease, your doctor may recommend regular monitoring. Otherwise, this test is usually done as needed for specific symptoms or medical decisions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy