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Antigen Detection for SARS-CoV-2 (COVID-19) by Rapid Immunochromatographic Assay (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of SARS-CoV-2 antigens in your blood, which may indicate an active COVID-19 infection. It uses a rapid immunoassay method to provide results quickly.

Quick summary

["Quickly checks for active COVID-19 infection using blood samples and a simple test strip method."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97099-6
Short code
FLUABV+SARS-CoV2 Ag Pnl Up resp IA.rapid
Synonyms
FLUABV+SARS-CoV2 Ag Pnl Up resp IA.rapid
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia-rapid
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test detects specific proteins (antigens) from the SARS-CoV-2 virus in your serum or plasma. When the virus is present, these antigens bind to antibodies in the test strip, creating a visible line or pattern. This reaction confirms whether you have an active infection.

What to Expect Before the Test

No special preparation is needed. You may have a blood draw from a vein, and the sample will be processed immediately to detect the antigens. Results are typically available within 15–30 minutes.

Limitations and Accuracy

This test is designed for rapid screening and may not detect all cases of COVID-19, especially if the infection is very early or has waned. It is not as accurate as PCR tests for confirming infection.

When This Test Might Be Used

Your healthcare provider may recommend this test for rapid assessment in settings like urgent care, workplace screening, or when immediate results are needed for travel or exposure control.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test helps identify active COVID-19 infections quickly, which is important for isolating individuals, guiding treatment decisions, and controlling outbreaks in communities. It is particularly useful for high-risk groups or situations where PCR testing is not immediately available.

Short name

COVID-19 Rapid Antigen Test (Serum/Plasma)

Frequently asked questions

Why might my test result be negative even if I suspect I have COVID-19?
A negative result could mean you don’t have an active infection, but it may also occur if the test was taken too early (before symptoms appear) or if the virus levels are too low to detect. If you develop symptoms later, consider retesting or getting a PCR test for confirmation.
Can this test detect COVID-19 in saliva instead of blood?
No, this specific test uses serum or plasma from a blood draw. Saliva-based antigen tests exist but are not the same as this immunoassay method.
How soon after exposure should I get tested for this antigen test?
Ideally, wait at least 2–5 days after potential exposure to increase the likelihood of detecting an active infection. However, results may vary depending on the timing of symptoms and viral load.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy