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Nucleic Acid Detection for SARS-CoV-2 (COVID-19) by Reverse Transcription Polymerase Chain Reaction (RT-PCR)

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from the SARS-CoV-2 virus, which causes COVID-19, using a nasal swab sample. It helps determine if you have an active infection.

Quick summary

["Identifies whether you currently have COVID-19 by detecting the virus’s genetic material."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
100345-8
Short code
FLUABV+SARS-CoV-2 RNA Pnl Spec NAA+probe
Synonyms
FLUABV+SARS-CoV-2 RNA Pnl Spec NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

A healthcare provider collects a sample from your nose using a swab. The swab is then sent to a lab where genetic material from the virus is extracted and analyzed. The test uses a process called reverse transcription polymerase chain reaction (RT-PCR) to identify the virus’s unique genetic sequence.

What to Expect Before the Test

You may experience mild discomfort or irritation when the swab is inserted, but it usually lasts only a few seconds. Avoid using nasal decongestants or sprays before the test, as they can affect results.

What to Expect After the Test

Most people do not experience any significant side effects. If you feel dizzy or have a sore throat afterward, it is likely due to the swab insertion and should resolve quickly. Follow up with your healthcare provider if you have concerns.

When This Test Is Needed

Your healthcare provider may recommend this test if you have symptoms of COVID-19 (such as fever, cough, or shortness of breath), have been exposed to someone with COVID-19, or are required for travel, work, or school purposes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a critical role in diagnosing active COVID-19 infections, guiding treatment decisions, and controlling the spread of the virus. Early detection helps prevent further transmission and allows for timely medical intervention if needed.

Short name

COVID-19 RT-PCR Test (Nasal Swab)

Frequently asked questions

Why might I need this test even if I don’t have symptoms?
You may need this test if you’ve been exposed to someone with COVID-19, are in a high-risk setting (like a healthcare facility or large gathering), or if your healthcare provider recommends it for monitoring or pre-exposure precautions.
How long does it take to get results?
Results are typically available within 24 to 72 hours, depending on the lab’s processing time. Some labs may offer same-day results under urgent circumstances.
Can I get this test at home?
Some at-home COVID-19 tests detect viral genetic material, but they are not the same as lab-based RT-PCR tests. Lab tests provide more accurate results and are typically used for confirmatory or large-scale screening.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy