Fluoroquinolone Resistance Phenotype by Mass Spectrometry (Serum/Plasma)

Why This Test Matters in Your Care

Fluoroquinolones are a class of antibiotics that work by stopping bacteria from replicating. However, some bacteria can develop resistance over time, making these drugs less effective. This test helps identify if a particular bacteria sample is resistant to fluoroquinolones, ensuring your treatment is as effective as possible.

How the Test Works

The test involves collecting a blood sample (serum or plasma) and analyzing it using mass spectrometry. This advanced technique detects the presence of specific genetic markers or proteins that indicate bacterial resistance to fluoroquinolones. It’s not a routine blood test but is used when doctors suspect resistance in a specific infection.

What to Expect Before the Test

You may not need special preparation for this test. If you’re having a blood draw for another reason, inform your healthcare provider about this test. Avoid eating or drinking for a short time before the blood draw if instructed, but this is not always required.

Common Uses and When It’s Ordered

This test is typically ordered when doctors suspect bacterial resistance to fluoroquinolones in infections such as urinary tract infections, pneumonia, or skin infections. It’s often used in cases where symptoms don’t improve with standard fluoroquinolone treatment or when bacteria have been previously exposed to these antibiotics.