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Fluorescent Immunoassay for Antibodies to Flavivirus Nucleocapsid Protein (IgG)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies to the nucleocapsid protein of flaviviruses, including viruses like dengue, Zika, or yellow fever, which may have recently infected you. It helps determine if your immune system has recognized these viruses.

Quick summary

["Assesses past exposure to flaviviruses through antibody detection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17013-4
Short code
FLUAV+FLUBV Ab Ser IF-aCnc
Synonyms
FLUAV+FLUBV Ab Ser IF-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fever, rash, joint pain, or neurological issues that could suggest flavivirus infection. It’s also used in outbreaks or after travel to high-risk areas. This test helps confirm whether your immune response was triggered by a flavivirus rather than another cause.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test looks for antibodies in your serum or plasma, which your body produces after exposure to flaviviruses.

What the Results Mean

A positive result means your immune system has detected antibodies to the flavivirus nucleocapsid protein, suggesting past exposure. A negative result indicates no detectable antibodies at this time. Results may take several days to return and should be interpreted by your healthcare provider.

Common Reasons for Testing

This test is often used in outbreaks, travel-related exposures, or when other tests (like dengue serology) are inconclusive. It helps differentiate between flaviviruses or rule out other infections causing similar symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

While this test confirms past exposure, it does not indicate active infection. If you’re experiencing symptoms, your doctor may order additional tests (like PCR or other serology) to determine if you’re currently ill. Antibody levels can change over time, so results may not be reliable if tested too soon or too late after exposure.

Short name

Flavivirus IgG Antibody (Nucleocapsid)

Frequently asked questions

Will this test show if I have an active infection right now?
No, this test detects antibodies formed after your body has already fought off a flavivirus infection. For active infection, your doctor may use a PCR test or other serology tests targeting different viral markers.
Can I get this test if I’ve never been tested before for flaviviruses?
Yes, but results may be less informative if you’ve had no prior exposure. This test is most useful if you’ve recently traveled to a high-risk area, had symptoms, or were exposed to flaviviruses.
How long does it take to get results from this test?
Results typically take 3–7 business days, depending on lab processing. Your healthcare provider will contact you once they’re ready. Always follow up with them for interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy