Skip to content

Fluorescent Immunoassay for Anti-Fluoroquinolone Antibodies (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies your immune system produces in response to fluoroquinolone antibiotics, a class of medications used to treat bacterial infections.

Quick summary

["Helps assess immune response to fluoroquinolone exposure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6434-5
Short code
FLUAV+FLUBV Ab Titr Ser IF
Synonyms
FLUAV+FLUBV Ab Titr Ser IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test detects specific antibodies (immunoglobulins) your body creates after exposure to fluoroquinolone antibiotics. These antibodies are part of your immune system’s defense against the medication’s effects, which can sometimes cause allergic reactions or other immune-related responses. The test uses a fluorescent immunoassay method to identify these antibodies in your serum sample.

Why It Might Be Ordered

Your healthcare provider may order this test if you’ve had a suspected allergic reaction, persistent symptoms, or if you’re being monitored for immune-related side effects after taking fluoroquinolone antibiotics. It can also help evaluate long-term exposure or potential immune-mediated complications.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The blood is processed to separate serum (the liquid part without clots), which is then tested for fluoroquinolone-specific antibodies. This process typically takes a few minutes, and you may experience a brief pinch or discomfort during the draw.

What to Expect Before the Test

No special preparation is needed for this test. You may eat and drink normally, but inform your provider if you’re taking any other medications or have conditions that might affect blood tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate your immune system has mounted an antibody response to fluoroquinolones, which may suggest hypersensitivity, chronic exposure, or immune-mediated effects. Negative results mean no detectable antibodies were found, indicating either no prior exposure or a very low immune response. This information can guide decisions about medication adjustments or further monitoring.

Short name

Anti-Fluoroquinolone Antibody Test

Frequently asked questions

When might I see this test ordered?
This test is often ordered after you’ve been exposed to fluoroquinolone antibiotics, particularly if you’ve experienced symptoms like rash, swelling, or other allergic reactions. It may also be used in research or specialized clinical settings to study immune responses to antibiotics.
What does a positive result mean?
A positive result means your body has produced antibodies against fluoroquinolone antibiotics, which could indicate an immune reaction. This doesn’t always mean you’re allergic, but it may prompt further evaluation by your healthcare provider.
Do I need to fast before this test?
No fasting is required for this test. However, always follow your provider’s instructions for any other tests you may have scheduled on the same day.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy