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Influenza Virus Rapid Antigen Test (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of viral antigens from the influenza virus in a blood sample to help diagnose recent infection.

Quick summary

["A rapid test to check for flu infection using your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72356-9
Short code
FLUAV + FLUBV Ag Spec IA.rapid
Synonyms
FLUAV + FLUBV Ag Spec IA.rapid
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia-rapid
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test uses a rapid immunoassay (fia) method to identify specific proteins (antigens) produced by the influenza virus shortly after infection. A small blood sample is collected, and antibodies in the test react with these antigens if present, producing a visible result within minutes.

What to Expect Before the Test

No special preparation is needed. You may have a blood draw at a clinic, doctor’s office, or lab. If done at home, follow the manufacturer’s instructions carefully.

What the Test Results Mean

A positive result indicates likely recent influenza infection. A negative result means the test did not detect the virus antigens at the time of testing, but infection could still be present if symptoms are severe or if testing was done too early. False negatives may occur if the test was done too soon after exposure.

When You Might Need This Test

Your healthcare provider may recommend this test if you have flu-like symptoms (fever, cough, sore throat) and suspect influenza, especially if you’re at higher risk for complications (e.g., elderly, immunocompromised, or pregnant). It can also be used in outbreak settings or for rapid screening in healthcare settings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test helps confirm influenza diagnosis quickly, guiding treatment decisions (e.g., antiviral medications) and reducing spread in communities. While not as sensitive as some viral tests, it is useful for initial screening due to its speed and simplicity. Results should be interpreted alongside clinical symptoms and patient history.

Frequently asked questions

Why did my provider order this test?
Your provider may have ordered this test to quickly assess for flu symptoms, especially if you’re at higher risk for complications or if flu activity is high in your area. It helps determine if antiviral treatment is needed early to reduce severity.
What does a positive result mean?
A positive result strongly suggests recent influenza infection. You may need to isolate to prevent spreading the virus to others and could benefit from antiviral medications if prescribed. Follow up with your provider for further guidance.
Can I get this test at home?
Yes, some rapid antigen tests for influenza are available over-the-counter for home use. These tests use a nasal or throat swab, not blood. If your provider ordered a blood-based test, it will be done in a clinical setting.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy