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Antibody to Flavivirus Nucleocapsid Protein (IgG) - Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against the nucleocapsid protein of flaviviruses, which include viruses like dengue, yellow fever, and West Nile. It helps determine if your immune system has encountered these viruses in the past.

Quick summary

["This test assesses past exposure to flaviviruses through antibody detection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6441-0
Short code
FLUAV+FLUBV+FLUCV Ag Spec Ql IA
Synonyms
FLUAV+FLUBV+FLUCV Ag Spec Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects IgG antibodies specific to the nucleocapsid protein of flaviviruses. These antibodies are produced by your immune system after an infection has cleared. The presence of these antibodies suggests prior exposure to one or more flaviviruses, though they may not indicate recent infection.

Why It Matters for You

Identifying past flavivirus exposure can be important for travelers, healthcare workers, or individuals in regions where these viruses are endemic. It helps guide vaccination decisions, monitor immune response, or assess risk in specific populations.

How the Test Works

Your blood sample is tested using a sensitive immunoassay method to detect IgG antibodies against the flavivirus nucleocapsid protein. This method is highly specific and reliable for detecting antibodies that your immune system has produced over time.

When You Might Need This Test

You may need this test if you’ve traveled to areas with flavivirus activity, have symptoms suggestive of a viral illness, or are part of a study evaluating immune responses to flaviviruses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Antibody to Flavivirus Nucleocapsid

Frequently asked questions

Why might my doctor order this test?
Your doctor may order this test to confirm past exposure to flaviviruses, assess immune response to vaccination, or evaluate risk in individuals with potential exposure. Antibody levels alone do not indicate current infection but can inform long-term health monitoring.
Can this test tell me if I have an active infection?
No, this test specifically looks for antibodies from past infections. For active infection, additional tests (like viral RNA detection) would be needed.
How long do flavivirus antibodies stay in my system?
Antibodies can persist for months to years after infection, but their exact duration varies by individual and virus. Follow-up testing may be recommended if needed for ongoing health decisions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy