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Fluorescent Immunoassay for Anti-Fluoroquinolone Antibodies in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies your immune system produces in response to fluoroquinolone antibiotics, a class of antibiotics used to treat bacterial infections.

Quick summary

["Helps assess immune response to fluoroquinolone exposure and potential allergic reactions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
82461-5
Short code
FLUAV+FLUBV+H1 09 pan RNA UpRes NAA+pr
Synonyms
FLUAV+FLUBV+H1 09 pan RNA UpRes NAA+pr
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test detects specific antibodies (immunoglobulins) your body creates when exposed to fluoroquinolone antibiotics. These antibodies are part of your immune system’s defense against the drug. The test uses a fluorescent immunoassay method, which is highly sensitive and specific for identifying these antibodies in your serum.

Why It Might Be Ordered

Your healthcare provider may order this test if you’ve had a suspected allergic reaction (such as rash, itching, or difficulty breathing) after taking fluoroquinolone antibiotics. It can also help evaluate whether your immune system has developed antibodies against these medications, which may influence future treatment decisions.

What to Expect Before the Test

No special preparation is typically needed. You may have a small needle inserted into your arm to draw blood. If you’re taking fluoroquinolone antibiotics, let your healthcare provider know before the test, as this may affect results.

What to Expect During the Test

The blood sample is collected in a tube and sent to a lab for analysis. The immunoassay process involves mixing the serum with labeled fluoroquinolone antibodies, which glow under special light to detect your immune response.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate your immune system has recognized fluoroquinolone antibiotics as foreign, potentially triggering allergic reactions. However, antibody presence alone doesn’t always mean you’ll experience symptoms. This test helps guide decisions about future antibiotic use, especially if you’ve had prior reactions.

Short name

Anti-Fluoroquinolone Antibodies (Serum)

Frequently asked questions

Will this test show if I have an allergy to fluoroquinolone antibiotics?
This test measures antibodies your body produces in response to fluoroquinolone exposure, which may correlate with an allergic reaction. However, antibodies alone don’t always predict symptoms. If you’ve had a reaction before, your doctor may use this test alongside clinical findings to assess risk.
What does a positive result mean?
A positive result suggests your immune system has detected fluoroquinolone antibodies, which could indicate prior exposure. It doesn’t confirm an allergy but may raise concerns if you’ve had symptoms like rash or breathing difficulties. Your doctor will interpret results in context with your medical history.
Can I still take fluoroquinolone antibiotics if this test is positive?
Not necessarily. A positive antibody test alone doesn’t rule out future use, but it may prompt your doctor to monitor you closely or choose alternative antibiotics. Always discuss risks and benefits with your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy