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Influenza Virus Nucleic Acid Detection by Nucleic Acid Amplification Test (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from the influenza virus in your blood, which helps determine if you have an active infection.

Quick summary

["Assists in diagnosing recent influenza infection through viral genetic detection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48509-4
Short code
FLUAV + FLUBV RNA Spec NAA+probe
Synonyms
FLUAV + FLUBV RNA Spec NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects fragments of the influenza virus’s genetic material (RNA) using a specialized probe. If the virus is present, the test can identify these fragments to confirm infection.

Why It’s Ordered

Your healthcare provider may order this test if you have symptoms like fever, cough, or sore throat and suspect you might have the flu, especially if you’re at higher risk for complications.

How the Test Works

A small blood sample is taken from your arm. The serum or plasma is then analyzed in a lab using a sensitive molecular technique to detect viral RNA. This process doesn’t require antibodies or antibodies to be present.

Sample Collection and Preparation

A healthcare professional will draw blood from a vein in your arm. The blood is processed to separate serum or plasma, which is then sent to the lab for testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for diagnosing influenza early, allowing for prompt treatment with antiviral medications that can reduce severity and shorten illness duration. It’s particularly useful for high-risk groups, such as the elderly or those with chronic health conditions.

Short name

Influenza Virus RNA Test

Frequently asked questions

How soon can I expect results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your provider will contact you once they have the results.
What does a positive result mean?
A positive result indicates the presence of influenza virus RNA in your blood, suggesting you have an active infection. This means you may have the flu and should seek medical advice for treatment options.
Can I still get the flu even if this test is negative?
Yes, a negative result means the test did not detect the virus at the time of testing. However, influenza can change or be less detectable in some cases, so symptoms may persist. If you continue to feel unwell, consult your healthcare provider for further evaluation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy