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Antibody to Flavivirus Nucleocapsid Protein (IgG) by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies against the nucleocapsid protein of flaviviruses, which are a group of viruses including dengue, yellow fever, and Zika. It helps identify past infection with these viruses.

Quick summary

["This test checks for immunity to flaviviruses from previous infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
77028-9
Short code
FLUAV H1 2009 pand RNA Nph Ql NAA+probe
Synonyms
FLUAV H1 2009 pand RNA Nph Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test measures the presence of IgG antibodies specific to the nucleocapsid protein of flaviviruses. These antibodies develop after an infection has cleared and indicate long-term immunity.

Why It’s Done

Healthcare providers may order this test to confirm past flavivirus infection in individuals who have had symptoms or exposure risk, such as travel to endemic regions or contact with infected individuals.

Sample Collection

A blood sample is collected from a vein in your arm. You may feel slight discomfort, but it usually takes a few minutes to complete. No special preparation is needed.

Test Process

The blood sample is processed to separate serum or plasma, which is then analyzed using an immunoassay method to detect flavivirus-specific IgG antibodies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results suggest past infection with flaviviruses, which can provide protection against future infections. This test is particularly useful in diagnosing flavivirus exposure in areas where these viruses are common, such as tropical and subtropical regions. It can also be used to assess immunity in travelers or individuals with potential exposure.

Short name

Anti-Flavivirus Nucleocapsid IgG

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 24 to 72 hours, depending on the laboratory’s processing schedule. Your healthcare provider will contact you once the results are ready.
Can this test detect active flavivirus infection?
No, this test specifically looks for antibodies produced after an infection has resolved. It does not detect active infection, which would require different diagnostic tests like viral RNA testing.
What does a positive result mean for my health?
A positive result indicates you likely had a flavivirus infection in the past and may have some level of immunity. However, it does not guarantee protection against future infections, especially if you have not been vaccinated or previously exposed. Consult your healthcare provider for guidance tailored to your situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy