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Fluorescent Immunoassay for Antinuclear Antibodies (ANA) with Probe-Based Detection

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies in your blood that may indicate an autoimmune condition, where your immune system mistakenly attacks healthy tissues.

Quick summary

["Helps identify possible autoimmune diseases by detecting abnormal antibodies targeting your body’s own cells."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55466-7
Short code
FLUAV H1 2009 pan RNA pnl Spec NAA+probe
Synonyms
FLUAV H1 2009 pan RNA pnl Spec NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is an ANA Test Used For?

ANA tests are often used as a screening tool for autoimmune diseases like lupus, rheumatoid arthritis, or other connective tissue disorders. They help doctors determine if your symptoms may be caused by an autoimmune reaction.

How Is the Test Performed?

A small blood sample is taken from your arm. The blood is then processed and exposed to antibodies that bind to specific parts of cells. Fluorescent dye marks any ANA present, allowing the test to detect them under a microscope.

What Does a Positive Result Mean?

A positive ANA result suggests an increased likelihood of an autoimmune condition, but it does not confirm a specific diagnosis. Further testing may be needed to narrow down the cause of your symptoms.

What Are Common Causes of Abnormal Results?

False positives can occur due to infections, certain medications, or other health conditions. ANA positivity alone does not diagnose an autoimmune disease—additional clinical evaluation and testing are required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: ANA Testing Plays a Key Role in Autoimmune Disease Diagnosis

Short name

ANA Fluorescent Test

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you have symptoms like joint pain, fatigue, rash, or unexplained organ issues that suggest an autoimmune condition. It helps rule out or confirm possible diagnoses before proceeding with further tests.
What if my ANA test is positive but I don’t have symptoms?
A positive ANA result doesn’t always mean you have an autoimmune disease. Some people test positive without symptoms, and monitoring may be needed. Your doctor will discuss next steps based on your overall health.
Can lifestyle changes affect ANA test results?
ANA levels can fluctuate over time, but they are not directly influenced by lifestyle changes like diet or exercise. If your results change, your doctor will assess whether further testing or follow-up is needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy