Hepatitis A Virus Antibody, Total (IgG + IgM) - Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the hepatitis A virus, which your body makes in response to infection. It helps determine if you’ve been exposed to the virus or if you have immunity.

Quick summary

["Hepatitis A antibodies help identify past infection or immunity to the virus."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC: 49519-2
Short code: FLUAV H16 Ab Titr Ser HAI
Synonyms: FLUAV H16 Ab Titr Ser HAI
Category: chemistry
Sample: serum
Container: Red-top tube (SST)
Units: N/A
Fasting: false
Population: adult
Sex: all
Age range: 18–65 years
Method: hai
Specimen volume: 5 mL
Stability: Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max: 500
Lipemia max: 1000
Icterus max: 500
TAT: 4–24 hours
Order: routine

Why This Test Is Done

Doctors may order this test to check for hepatitis A infection, especially if you’ve traveled to areas with higher risk, had unprotected exposure, or have symptoms like fever, fatigue, or jaundice. It can also help confirm immunity after vaccination or diagnose past infection.

What to Expect Before the Test

No special preparation is needed. You’ll likely have a small needle inserted into your arm to draw blood. If you’re concerned about needles, let your healthcare provider know so they can provide reassurance or alternative options.

What the Test Results Mean

Positive results for IgM antibodies suggest recent infection. Positive IgG antibodies indicate past infection or immunity. A test for both IgG and IgM together helps confirm exposure or immunity status.

Possible Symptoms of Hepatitis A

Hepatitis A often causes mild symptoms like nausea, fatigue, or jaundice (yellowing of skin/eyes), but many people don’t notice anything. Severe cases can occur, especially in adults.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Understanding Your Results

Short name

Hep A Antibody Total

Frequently asked questions

If your results show IgM antibodies, you likely had hepatitis A recently and should avoid sharing food or drinks with others to prevent spreading the virus. If IgG antibodies are present, you have immunity and can safely share items with others.

IgM antibodies alone indicate an active infection that needs monitoring. IgG antibodies alone suggest immunity from past infection or vaccination, but you should still practice good hygiene to avoid future exposure.

What if I’ve been vaccinated? Will this test show immunity?

Yes, if vaccinated, your test may show IgG antibodies, confirming immunity. Vaccination provides long-term protection, so you won’t need this test unless you’re unsure about your vaccination status or have symptoms.

Can I get hepatitis A from food or water?

Yes, hepatitis A spreads through contaminated food or water. Practice food safety—wash hands before cooking, avoid raw shellfish, and cook food thoroughly to reduce risk.

Sources

1
MedlinePlus — Laboratory TestsSource
2
Lab Tests OnlineSource
3
Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy