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Fluorescent Immunoassay for Antinuclear Antibodies (ANA) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures a type of antibody your immune system produces when it mistakenly targets healthy cells in your body, often linked to autoimmune diseases.

Quick summary

["Helps diagnose conditions like lupus or other autoimmune disorders by detecting antibodies against your own tissues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94396-9
Short code
FLUAV H1 RNA Lower resp Ql NAA+probe
Synonyms
FLUAV H1 RNA Lower resp Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Antinuclear antibodies (ANA) are proteins your immune system makes that can attack healthy cells in your joints, skin, blood vessels, or other organs. This test checks for their presence in your blood, which can signal an autoimmune condition like lupus, rheumatoid arthritis, or scleroderma.

How the Test Works

A small sample of your blood is taken and tested using a fluorescent immunoassay. Fluorescent dyes bind to ANA if they’re present, making them visible under a microscope to detect their presence.

Common Conditions Monitored

Positive results may indicate autoimmune diseases, but they’re not definitive. Other tests and symptoms are needed to confirm a diagnosis.

What to Expect Before the Test

No special preparation is needed. You may have a slight bruise or soreness at the blood draw site, but this usually fades quickly.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

ANA testing is a key screening tool for autoimmune diseases. While many people with ANA have no symptoms, elevated levels can signal inflammation or organ damage. Results help doctors guide further testing or treatment plans.

Short name

ANA Fluorescence Probe Test

Frequently asked questions

What does a positive ANA test mean?
A positive ANA test means your immune system may be producing antibodies against your own cells, which can be a sign of an autoimmune condition. However, many people with positive results never develop symptoms or a diagnosis.
Can I get this test at home?
No, this test is typically done in a lab using a blood sample drawn by a healthcare provider. Home tests for ANA are not standard or reliable for clinical use.
How long does it take to get results?
Results are usually available within 1–3 business days, depending on your lab’s processing time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy