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Antibody to Flavivirus Nucleocapsid Protein (IgG) - Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against the nucleocapsid protein of flaviviruses, which include viruses like dengue, yellow fever, and Zika. It helps determine if your body has been exposed to these viruses.

Quick summary

["This test helps identify past infection with flaviviruses, aiding in diagnosis and understanding exposure history."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74039-9
Short code
FLUAV H3 RNA Ct Spec Qn NAA+probe
Synonyms
FLUAV H3 RNA Ct Spec Qn NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects IgG antibodies specific to the nucleocapsid protein of flaviviruses. These antibodies are produced by your immune system in response to infection. The presence of these antibodies suggests prior exposure to one of these viruses, though they may not always indicate an active infection.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms suggestive of flavivirus infection (e.g., fever, headache, rash) or if you have traveled to or lived in areas where flaviviruses are common. It can also be used for research or epidemiological studies.

How the Test Works

A small blood sample is taken from your arm. The serum portion of the blood is then tested using an immunoassay method to detect the presence of IgG antibodies against the flavivirus nucleocapsid protein.

What to Expect Before the Test

No special preparation is needed for this test. You may have a slight bruise or soreness at the injection site, but this usually resolves quickly. If you are on blood-thinning medication, let your provider know before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Antibody to Flavivirus Nucleocapsid

Frequently asked questions

Will this test show if I currently have a flavivirus infection?
No, this test only detects antibodies produced after an infection has occurred. It does not measure active virus presence or show if you have an ongoing infection. Active infection would typically require additional testing, such as viral RNA detection or other serological tests.
Can I get this test if I haven’t traveled to a flavivirus-endemic area?
Yes, this test can be used for research, general screening, or if you have symptoms suggestive of flavivirus exposure, regardless of travel history. Your healthcare provider will determine if this test is appropriate for your situation.
How long will it take to get my results?
Results are typically available within a few days to a couple of weeks, depending on the lab’s processing time. Your healthcare provider will contact you with the results once they are ready.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy