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Fluorescent Immunoassay for Antinuclear Antibodies (ANA) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies your immune system may produce against parts of your own cells, often linked to autoimmune conditions.

Quick summary

["Helps identify possible autoimmune diseases by detecting unusual antibodies in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92808-5
Short code
FLUAV H3 RNA Upper resp Ql NAA+probe
Synonyms
FLUAV H3 RNA Upper resp Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses a special probe to detect the presence of antinuclear antibodies (ANA) in your serum. These antibodies target components inside your cells, which can signal an immune response against healthy tissue.

How the Test Works

A small sample of your blood is sent to a lab where it is mixed with cells that have been treated to highlight their internal structures. Fluorescent dye binds to any ANA present, making them visible under a microscope.

Why It’s Done

Doctors may order this test if you have symptoms like joint pain, fatigue, or unexplained rashes, or if they suspect conditions like lupus, rheumatoid arthritis, or other autoimmune disorders.

Possible Results

A positive result means antibodies were found, which may indicate an autoimmune condition. However, a negative result does not definitively rule out these diseases.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

ANA Fluorescence Test

Frequently asked questions

Why might I need this test?
Your doctor may recommend it if you have symptoms like persistent fatigue, joint swelling, or unexplained skin rashes, or if they suspect an autoimmune disease.
What does a positive result mean?
A positive result means your blood contains antibodies against cell components, which may signal an autoimmune response. Further testing is usually needed to determine the exact cause.
Can I eat or drink before this test?
You can eat and drink normally before this test, as it only requires a blood sample. No special preparation is needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy