Skip to content

Influenza Nucleic Acid Detection by Probe-Based Assay (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic material from the influenza virus in your blood, which may indicate an active infection.

Quick summary

["Detects recent influenza infection through viral RNA presence in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38272-1
Short code
FLUAV H5 RNA Spec Ql NAA+probe
Synonyms
FLUAV H5 RNA Spec Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

How the Test Works

The test uses a specialized probe to identify fragments of the influenza virus’s genetic material (RNA) in your serum or plasma. If the virus is present, the probe will bind to its RNA, allowing the test to confirm infection.

What to Expect Before the Test

No special preparation is needed. You may have a blood draw at your doctor’s office or lab. If you’re experiencing flu-like symptoms, this test can help determine if the illness is caused by the influenza virus.

When This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fever, cough, sore throat, or body aches—especially if you’re in a high-risk group for influenza (e.g., elderly, immunocompromised, or pregnant). It’s also used during outbreaks or when rapid diagnosis is needed.

Limitations and Considerations

This test detects viral RNA but does not confirm if you’re contagious or how severe your illness will be. False negatives can occur if the virus is still replicating or if the sample is collected too early. Results may not be available immediately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Influenza Virus RNA Test

Frequently asked questions

Why might my doctor order this test?
To confirm if your symptoms are caused by influenza, especially if other tests (like rapid flu tests) were inconclusive or if you’re at higher risk for complications. It helps guide treatment decisions, such as antiviral medications.
What does a positive result mean?
A positive result means your blood contains genetic material from the influenza virus, suggesting you have an active infection. This does not indicate the exact type of influenza (A or B), but it confirms the virus is present.
How soon will I need to start treatment if my test is positive?
If your test is positive, your doctor may recommend antiviral medications within 48 hours of symptom onset for the best chance of reducing symptoms and complications. Treatment timing depends on your symptoms, overall health, and other factors discussed with your provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy