Serum or plasma concentration of flavoprotein (e.g., flavin adenine dinucleotide, FAD) by high-performance liquid chromatography (HPLC)

What Flavins Are and Their Role in the Body

Flavins, including flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), are coenzymes that help enzymes transfer electrons during metabolism. They play a key role in energy production, particularly in mitochondria, where they assist in the breakdown of nutrients into usable energy. Abnormal levels might suggest metabolic dysfunction or other underlying conditions.

How the Test Works

Your blood sample is analyzed using high-performance liquid chromatography (HPLC), a precise method that separates and quantifies flavin compounds. This test helps assess whether your body has adequate levels of these essential molecules for normal metabolic function.

When This Test Might Be Ordered

A flavin concentration test may be recommended if you have symptoms of metabolic disorders, such as fatigue, weakness, or unexplained weight changes. It could also be part of a broader evaluation for conditions affecting mitochondrial function or nutrient absorption.

What to Expect Before the Test

No special preparation is typically required, but you may need to fast for a few hours before the test if instructed by your healthcare provider. Wear comfortable clothing for blood draw, and inform your doctor about any medications or supplements you take.