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Antibody to Flavivirus (e.g., Dengue, Yellow Fever) IgM by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test detects IgM antibodies against flaviviruses, which are viruses like dengue or yellow fever. It helps identify if you’ve recently been infected.

Quick summary

["IgM antibodies appear early in infection and can help diagnose recent flavivirus exposure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49527-5
Short code
FLUAV H7 RNA Islt Ql NAA+probe
Synonyms
FLUAV H7 RNA Islt Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for IgM antibodies specific to flaviviruses, which are a group of viruses transmitted by mosquitoes. These antibodies develop shortly after infection and can indicate a recent exposure to viruses such as dengue, yellow fever, or others in this family. The presence of IgM antibodies is often used to diagnose acute infection, especially when combined with clinical symptoms and other diagnostic criteria.

Why It Matters in Diagnosis

IgM antibodies are typically detected within days to weeks after infection begins. They can help doctors confirm a recent flavivirus infection, particularly in cases where symptoms like fever, headache, or muscle pain are present. This test is often used alongside other tests or clinical findings to guide treatment and management.

Sample Collection and Preparation

This test uses a blood sample, usually taken from a vein in your arm. The blood is processed to separate serum or plasma, which is then analyzed using an immunoassay method to detect IgM antibodies. The sample is typically sent to a laboratory for testing.

When You Might Need This Test

Your healthcare provider may recommend this test if you have symptoms of a viral illness, such as fever, rash, joint pain, or headache, and have recently traveled to or lived in an area where flaviviruses are common. It may also be used in outbreaks or during investigations of suspected cases.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

IgM antibodies to flaviviruses are useful for diagnosing recent infections, especially when other diagnostic tests are inconclusive. They are particularly important in areas where flaviviruses are endemic or during outbreaks. However, IgM levels can decrease over time, so this test is most reliable for diagnosing acute infection. It is often used alongside IgG testing to distinguish between recent and past infections.

Short name

Flavivirus IgM Antibody

Frequently asked questions

What does a positive result mean?
A positive result suggests you may have recently been infected with a flavivirus, such as dengue or yellow fever. This can help your healthcare provider confirm the diagnosis and guide treatment or further testing if needed.
Can IgM antibodies stay in my system long after infection?
IgM antibodies typically decline over weeks to months after infection. They are not usually detected long-term, but they can persist longer in some individuals. IgG antibodies, which develop later, may remain detectable for longer periods and can indicate past infection.
Is this test sensitive to false positives?
While the test is generally reliable, there is a very low chance of false positives, especially if cross-reactivity with other viruses occurs. Your healthcare provider will consider clinical symptoms, travel history, and other test results to interpret the results accurately.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy