Fluoroquinolone (e.g., ciprofloxacin, levofloxacin) Concentration in Cerebrospinal Fluid by Mass
This test measures the amount of certain antibiotics (fluoroquinolones) in your cerebrospinal fluid (CSF). These drugs are sometimes used to treat serious infections in the central nervous system, such as meningitis.
["Knowing your antibiotic levels helps doctors determine if the treatment is working and adjusts dosing if needed."]
Key facts at a glance
- LOINC
- 49074-8
- Short code
- FLUAV IgA CSF-mCnc
- Synonyms
- FLUAV IgA CSF-mCnc
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you have or are suspected of having a bacterial infection in the brain or spinal cord (e.g., meningitis). Fluoroquinolones are often prescribed for these conditions, and monitoring their levels helps ensure proper dosing and effectiveness.
What to Expect Before the Test
No special preparation is usually needed. You may receive a local anesthetic to numb the area where the needle will be inserted. The test involves a small sample of CSF being taken through a procedure called a lumbar puncture (spinal tap).
What the Test Results Mean
Results show the concentration of fluoroquinolone in your CSF. Low levels may indicate insufficient treatment, while very high levels could suggest toxicity or improper dosing. Your doctor will interpret these results in the context of your medical history and symptoms.
Potential Side Effects or Risks
The most common risk is temporary pain or discomfort at the injection site. Rarely, complications like headaches, dizziness, or infection may occur. Always inform your doctor about any allergies or concerns before the procedure.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated fluoroquinolone levels in CSF confirm adequate antibiotic penetration into the central nervous system, which is critical for treating infections like meningitis. Low levels may prompt adjustments to dosage or choice of antibiotic. Monitoring helps prevent overuse or underuse of these powerful medications.
Short name
Fluoroquinolone CSF Level
Frequently asked questions
What does a normal or abnormal result mean?
How often will I need this test?
Can I eat or drink before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy