Influenza A/B Nucleic Acid Detection (Real-Time Polymerase Chain Reaction)

How the Test Works

A small sample of your nasal or throat secretions is collected using a swab. The swab is then sent to a lab where special equipment detects the virus’s genetic material using real-time PCR. This process identifies whether influenza A or B is present without needing to grow the virus in a lab.

What to Expect During the Test

You’ll likely have a quick, painless procedure where a healthcare provider inserts a swab into your nose or throat. No special preparation is needed, but avoid eating, drinking, or smoking for 15 minutes before the test if instructed.

When You Might Need This Test

Your doctor may order this test if you have flu-like symptoms (fever, cough, sore throat, body aches) and suspect you have the flu, especially if you’re in a high-risk group (e.g., young children, elderly adults, or those with chronic health conditions).

What the Results Mean

Positive results indicate the presence of influenza virus RNA, confirming an active infection. Negative results mean the virus isn’t detected at the time of testing, but you may still have the flu or it could take time for the virus to be detected.